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Lodoxamide - CAS# 53882-12-5 size:2mg solid orally active

SKU: 93996450095

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Lodoxamide - CAS# 53882-12-5 size:2mg solid orally activeLodoxamide, CAS No. 53882 12 5, is a potent agonist of GPR35 with an EC50 value of 1. 61 nM in a arrestin 2 interaction assay using CHO K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48 80 (Item No. 22173), anti IgE, or A23187 (Item No. 11016) in isolated rat peritoneal mast cells (IC50s = 0. 1 50 M) and inhibits A23187 induced calcium influx in mast cells. It reduces antigen induced histamine release from

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Description

orally active

Shelf Life: ≥24 months if stored properly

48208-26-0

Epub 2016 Jun 21

Connolly EC

Lodoxamide - CAS# 53882-12-5 size:2mg solid orally activeLodoxamide, CAS No. 53882 12 5, is a potent agonist of GPR35 with an EC50 value of 1. 61 nM in a arrestin 2 interaction assay using CHO K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48 80 (Item No. 22173), anti IgE, or A23187 (Item No. 11016) in isolated rat peritoneal mast cells (IC50s = 0. 1 50 M) and inhibits A23187 induced calcium influx in mast cells. It reduces antigen induced histamine release from

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