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MLN4924 Hydrochloride - CAS# 1160295-21-5 Catalog No.:M10954-10 validating IKK-2 as a potential

MLN4924 Hydrochloride - CAS# 1160295-21-5 Catalog No.:M10954-10 validating IKK-2 as a potential

Name: MLN4924 Hydrochloride - CAS# 1160295-21-5 Catalog No.:M10954-10 validating IKK-2 as a potential
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MLN4924 Hydrochloride - CAS# 1160295-21-5 Catalog No.:M10954-10 validating IKK-2 as a potentialPevonedistat, also known as MLN 4924 and TAK 924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. NAE activates Nedd8 (Neural precursor cell expressed, developmentally down regulated 8), an ubiquitin like (UBL) protein that modifies cellular targets in a pathway that is

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Description

validating IKK-2 as a potential anti-inflammatory drug target in vivo

SB-269970A

Mizolastine is a selective histamine H1 receptor antagonist

271 and PF-271

also known as Lu-28-179

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