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Fenretinide - CAS# 65646-68-6 127 Vesnarinone improves ventricular performance most

Fenretinide - CAS# 65646-68-6 127 Vesnarinone improves ventricular performance most

Name: Fenretinide - CAS# 65646-68-6 127 Vesnarinone improves ventricular performance most
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Fenretinide - CAS# 65646-68-6 127 Vesnarinone improves ventricular performance mostFenretinide, CAS No. 65646 68 6, is an orally active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis associated growth factors and their receptors and exhibits retinoid

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Description

Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure

Zajac-Kaye M

(2008) J Med Chem

PubMed PMID: 21940661

4SC-202 was used at 10µM final concentration in various in vitro assays

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