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Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid Solubility: DMSO: 77 mg/mL (185

Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid Solubility: DMSO: 77 mg/mL (185

Name: Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid Solubility: DMSO: 77 mg/mL (185
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SKU: 66049962358

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Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid Solubility: DMSO: 77 mg/mL (185Remodelin, CAS No. 949912 58 7, is a novel potent and selective inhibitor of the acetyl transferase protein NAT10. It can improve nuclear architecture, chromatin organization, and fitness of both human lamin A C depleted cells and HGPS derived patient cells, and decrease markers of DNA damage in these cells. Using a combination of chemical, cellular, and genetic approaches, acetyl transferase protein NAT10 was identified as the target of Remodelin

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Solubility: DMSO: 77 mg/mL (185

and pancreatic cancers

2-dihydro-3H-pyrazolo[3

Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2

4SC-202 shows a broad anti-proliferative activity towards human cancer cell lines with a mean IC50 of 0

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