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TBPB Catalog No.:M10385-10 It has been shown to

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TBPB Catalog No.:M10385-10 It has been shown toTBPB is a highly selective Muscarinic M1 receptor allosteric agonist. TBPB activates M1 through an allosteric site rather than the orthosteric acetylcholine binding site, which is likely critical for its selectivity. TBPB displays unprecedented functional selectivity at the M mAChR. TBPB is a bitopic ligand, interacting with both the orthosteric site and an allosteric site, at the M mAChR. Product information CAS Number: 634616 95 8 Molecular Weight:

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Description

It has been shown to produce sedative and anorectic effects in animals

or pelvic inflammatory disease

Chemical Name: N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2

having MTDs in mice and rats of >150 mg/ kg and 90 mg/kg in rats

¹⁶]hexadeca-1(16)

TBPB Catalog No.:M10385-10 It has been shown toTBPB is a highly selective Muscarinic M1 receptor allosteric agonist. TBPB activates M1 through an allosteric site rather than the orthosteric acetylcholine binding site, which is likely critical for its selectivity. TBPB displays unprecedented functional selectivity at the M mAChR. TBPB is a bitopic ligand, interacting with both the orthosteric site and an allosteric site, at the M mAChR. Product information CAS Number: 634616 95 8 Molecular Weight:

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