Azeliragon HCl - CAS# 1284150-65-7 66049 Tempostatin

Tempostatin

Chemical Name:  5-((5-chloro-1H-pyrrolo[2

8°C at 130 min post injection

GRP-60367 inhibits entry of a subset of RABV strains

Effects of ticlopidine on pharmacokinetics of losartan and its main metabolite EXP3174 in rats

Azeliragon HCl - CAS# 1284150-65-7 66049 TempostatinAzeliragon HCl, CAS No. 1284150 65 7, also known as TTP488 and PF 04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for