Triapine - CAS# 143621-35-6 0264 a class III HDAC inhibitor

a class III HDAC inhibitor

twice daily) causes an inhibition of tumor growth in NCr athymic mice bearing established SW620 human colorectal cancer xenografts

also known as SM04690

Smiles: COC1=CC2=NC=NC(NC3=CC=CC(=C3)C#C)=C2C=C1OCCCCCCC(=O)NO

it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self-renewal properties

Triapine - CAS# 143621-35-6 0264 a class III HDAC inhibitorTriapine, also known as 3 AP and OCX 191, CAS No. 143621 35 6, is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. Product information CAS Number: 143621 35 6