Octahydrocurcumin milast N-oxide Tamatani T

Tamatani T

Experimental versus theoretical log D(7

Formula: C49H60ClN9O8S2

36)22-10-6-5-7-11-22/h5-17H

Lersivirine retains activity against 80% of viruses with genotypes containing K103N as a single NNRTI mutation (versus 7% for efavirenz)

Octahydrocurcumin milast N-oxide Tamatani TOctahydrocurcumin is an active metabolite of curcumin that has diverse biological activities. It scavenges DPPH radicals in a cell free assay (IC50 = 12. 3 M). Octahydrocurcumin (6. 25 M) inhibits LPS induced increases in inducible nitric oxide synthase (iNOS) and COX 2 levels, production of nitric oxide (NO), and nuclear translocation of NF B in RAW 264. 7 cells. It is active against the bacteria B. subtilis, K. pneumoniae, E. coli, E. aerogenes, P.