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Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome CCBP2 is expressed in a

SKU: 99971484967

4.1
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Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome CCBP2 is expressed in aBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

CCBP2 is expressed in a range of tissues and hemopoietic cells

and gamma subunits in a 1:1:1 ratio

The protein has four IQ motifs located in the neck domain that bind calmodulin

Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1

This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids

Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome CCBP2 is expressed in aBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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