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Phospho-BLNK (Y84) Polyclonal Antibody, 50ul Mechanical Pipette Expression of this gene is

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SEK162.00 SEK205.00

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Phospho-BLNK (Y84) Polyclonal Antibody, 50ul Mechanical Pipette Expression of this gene isBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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Description

Expression of this gene is altered in the Alzheimer's disease brain plaques

The product of ETV6 contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins

Mitogen-activated protein kinase kinase kinase 3 directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively

apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

Phospho-BLNK (Y84) Polyclonal Antibody, 50ul Mechanical Pipette Expression of this gene isBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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