Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been found for HRH2

the biological significance of the two forms is not known

It functions as a receptor for endogenous ligands

Mutations in this gene cause Alexander disease

Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking| intracellular motility| organelle biogenesis| protein folding| and proteolysis

Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets Alternatively spliced transcript variants encodingThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The