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CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging The predicted protein is proline-rich

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CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging The predicted protein is proline-richCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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Description

The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains

suggesting an important role of this protein during integrin-dependent cell adhesion

Alternatively spliced transcript variants have been found for PTTG1IP

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors

MIM 313650) comprises the TATA box-binding protein (TBP

CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging The predicted protein is proline-richCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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