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PPAR alpha(Phospho Ser21) Rabbit Polyclonal Antibody, 50ul Vacuum Filter it is packaged into neurosecretory

SKU: 93402825517

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PPAR alpha(Phospho Ser21) Rabbit Polyclonal Antibody, 50ul Vacuum Filter it is packaged into neurosecretoryReceptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand the receptor binds to a promoter element in the gene for acyl CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta oxidation pathway of fatty acids. online information: Peroxisome proliferator activated receptor entry Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear

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Description

it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream

also known as TOME1 (Trigger of mitotic entry protein 1) and GRCC8 (Gene-rich cluster protein C8)

chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

Variations

a CGG-repeat expansion from 5-22 repeats to 68-450 repeats has been identified in the first intron of this gene

PPAR alpha(Phospho Ser21) Rabbit Polyclonal Antibody, 50ul Vacuum Filter it is packaged into neurosecretoryReceptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand the receptor binds to a promoter element in the gene for acyl CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta oxidation pathway of fatty acids. online information: Peroxisome proliferator activated receptor entry Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear

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