PBF Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein is a

The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity

Pseudogenes exist on chromosomes 7 and 8

This gene encodes a member of the SH2B adaptor family of proteins

while defects in this gene are associated with multiple types of cancer

Additional variants have been observed| but their full-length natures have not been determined

PBF Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein is aPTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.