VEGF Receptor 2(Phospho-Tyr1175) Rabbit Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in SLC4A11 have been

Mutations in SLC4A11 have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

important for removing glucose from the bloodstream into skeletal muscle and fat tissues

Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1

The activity of the encoded protein is regulated by polo-like kinase 1

VEGF Receptor 2(Phospho-Tyr1175) Rabbit Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in SLC4A11 have beenVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors