MLKL mouse Monoclonal Antibody(8H7), 20ul Roller Bottles There are two transcripts identified

There are two transcripts identified for this gene

IFNL1 encodes a cytokine distantly related to type I interferons and the IL-10 family

This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases

2003 [PubMed 12963707])

Mutations associated with this gene cause autosomal recessive spastic paraplegia 13

MLKL mouse Monoclonal Antibody(8H7), 20ul Roller Bottles There are two transcripts identifiedThis gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase like domain however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF) induced necroptosis, a programmed cell death process, via interaction with receptor interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor