KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression Mutations in this gene have

Mutations in this gene have been associated with medulloblastomas

Gene Ontology (GO) annotations related to this gene include transferase activity

is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain

a protein essential for cell cycle progression through the G2/M transition

four ANK repeats and 11 leucine-rich repeats and belongs to the Ser/Thr protein kinase family

KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression Mutations in this gene haveAction potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by