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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Alterations in levels of the

SKU: 88525901458

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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Alterations in levels of thedisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

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Description

Alterations in levels of the encoded protein may be associated with many diseases

This cyclin binds both CDK2 and CDC2 kinases

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development

100% integrity test Sterilized and non-sterilized available

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Alterations in levels of thedisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

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