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HCN4 Polyclonal Antibody, 100ul Custom RNA Oligos cytoplasmic proteins that bind long-chain

SKU: 87242589309

4.2
EUR141.00 EUR191.00

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HCN4 Polyclonal Antibody, 100ul Custom RNA Oligos cytoplasmic proteins that bind long-chainThis gene encodes a member of the hyperpolarization activated cyclic nucleotide gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes

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Description

cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands

Amplification and overexpression of this gene are also associated with multiple human cancers

The encoded protein has been shown to be capable of interacting with several GPCRs

Multiple splice variants encoding different isoforms have been found for this gene

The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S)

HCN4 Polyclonal Antibody, 100ul Custom RNA Oligos cytoplasmic proteins that bind long-chainThis gene encodes a member of the hyperpolarization activated cyclic nucleotide gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes

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