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Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes frequently with sex reversal

SKU: 85742471769

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Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes frequently with sex reversalThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

frequently with sex reversal

Alternative splicing results in multiple transcript variants encoding differerent isoforms

A pseudogene of RFC2 has been defined on chromosome 2

Alternatively spliced transcript variants have been described for this gene

each enriched in postsynaptic density preparations relative to brain homogenate

Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes frequently with sex reversalThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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