Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification The two variants are differentially

The two variants are differentially expressed in embryonic tissues

The encoded enzyme (carbohydrate sulfotransferase 2) catalyzes the sulfation of a nonreducing N-acetylglucosamine residue

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

A spliced antisense transcript of AVPR1B has been reported but its function is not known

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Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification The two variants are differentiallyLFNG is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked fucose