ATS13 Polyclonal Antibody, 50ul Antibody Humanization The L isoform is expressed

The L isoform is expressed only in hemopoietic cell lineages| while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts| endothelial cells| epithelial cells| melanocytes| etc

signal transduction

The encoded protein has four extracellular C2-type immunoglobulin domains

The protein encoded by this gene is a non-lineage-restricted

allowing ions to move through the pore

ATS13 Polyclonal Antibody, 50ul Antibody Humanization The L isoform is expressedThis gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.