MARH7 Polyclonal Antibody, 20ul Antibody Humanization The nuclear export signal is

The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR

This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis

Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described

Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence

which include cyclin A

MARH7 Polyclonal Antibody, 20ul Antibody Humanization The nuclear export signal isMARCH7 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004