RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The 3-phosphoinositide dependent protein kinase-1

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex

with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters

The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13

The protein has been implicated in the development of Alzheimer disease

RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The 3-phosphoinositide dependent protein kinase-1RFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have