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AZ1 Polyclonal Antibody, 100ul Reservoirs The protein encoded by this

SKU: 81371342397

4.5
DKK123.75 DKK152.75

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AZ1 Polyclonal Antibody, 100ul Reservoirs The protein encoded by thisThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1

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Description

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins

Capacity:5/15mL × 28

Tumor suppressor

An important paralog of this gene is DNAL4

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

AZ1 Polyclonal Antibody, 100ul Reservoirs The protein encoded by thisThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1

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