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Phospho-AR (S94) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds Atypical Ras-like protein that acts

SKU: 80446335553

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Phospho-AR (S94) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds Atypical Ras-like protein that actsThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals

SNF1 subfamily

It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation

It has been shown to interact with

The TNF receptor superfamily member 13B encoded by TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily

Phospho-AR (S94) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds Atypical Ras-like protein that actsThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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