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NBEAL1 Polyclonal Antibody, 50ul Low retention tips This protein binds both the

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NBEAL1 Polyclonal Antibody, 50ul Low retention tips This protein binds both theNBEAL1 (neurobeachin like 1), also known as ALS2CR16 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) or ALS2CR17, is a 2694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes

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Description

This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin| and it appears to play a role in calcium homeostasis in the ER

Also phosphorylated on Ser-524 independently of reelin signaling

This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts

GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

ERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases

NBEAL1 Polyclonal Antibody, 50ul Low retention tips This protein binds both theNBEAL1 (neurobeachin like 1), also known as ALS2CR16 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) or ALS2CR17, is a 2694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes

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