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KPYR Polyclonal Antibody, 100ul RNA Synthesis proteins and membranes are transported

SKU: 78724054690

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KPYR Polyclonal Antibody, 100ul RNA Synthesis proteins and membranes are transportedThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

proteins and membranes are transported to the endosome where they are sorted for recycling or degradation

but studies of other populations have not been able to replicate this association

This protein binds F-actin| and also interacts with 5-lipoxygenase| which is the first committed enzyme in leukotriene biosynthesis

Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease

Gene Ontology (GO) annotations related to this gene include calcium channel activity

KPYR Polyclonal Antibody, 100ul RNA Synthesis proteins and membranes are transportedThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

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