FGF-BP2 Polyclonal Antibody, 50ul Lysosome May be involved in up-regulation

May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2

Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter

FGF-BP2 Polyclonal Antibody, 50ul Lysosome May be involved in up-regulationFGFBP2 (fibroblast growth factor binding protein 2) encodes a member of the fibroblast growth factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.