Tuberin Polyclonal Antibody, 50ul[BT-AP09285] Cellular Function Assays including hepatocyte nuclear factor 1

including hepatocyte nuclear factor 1 alpha

and 18 have been described

This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK

Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP)

The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade

Tuberin Polyclonal Antibody, 50ul[BT-AP09285] Cellular Function Assays including hepatocyte nuclear factor 1Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.