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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The functional domains of p53

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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The functional domains of p53This gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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Description

The functional domains of p53 family proteins include an N-terminal transactivation domain

The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism

where it may contribute to insulin resistance in glucose uptake

Yeast two-hybrid studies found ULK1/2 associated with modulators of the endocytic pathway

It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demeth-oxygeldanamycin

Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The functional domains of p53This gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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