R51A1 Polyclonal Antibody, 50ul Biochemical Reagents The CCR4-NOT complex plays a

The CCR4-NOT complex plays a role in many cellular processes| including miRNA-mediated repression| mRNA degradation| and transcriptional regulation

The encoded protein may be involved in the activation of lymphoid cells and support testicular functions

Three subunits (alpha| beta and gamma) of the 11S regulator have been identified

The full-length nature of some variants has not been determined

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R51A1 Polyclonal Antibody, 50ul Biochemical Reagents The CCR4-NOT complex plays aalternative products: Additional isoforms seem to exist,May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location: Colocalizes with RAD51 to multiple nuclear foci.,subunit: Isoform 2 interacts