Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos CABC1 expression is induced both

CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53

which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies

particularly in cells of the myeloid and B-lymphoid lineages

and in the subsequent clustering of the acetylcholine receptor in myotubes

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells

Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos CABC1 expression is induced bothRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.