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DNAM-1 Polyclonal Antibody, 100ul[BT-AP02671] Antisense Oligonucleotides The protein is found predominantly

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DNAM-1 Polyclonal Antibody, 100ul[BT-AP02671] Antisense Oligonucleotides The protein is found predominantlyCD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig superfamily containing 2 Ig like domains of the V set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

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Description

The protein is found predominantly in the nucleus| although it is also present in the cytoplasm

CPN1 encodes the catalytic subunit

Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene

This member is a delayed rectifier potassium channel and its activity is modulated by some other family members

Mutations in this gene are a cause of autism spectrum disorder (ASD)

DNAM-1 Polyclonal Antibody, 100ul[BT-AP02671] Antisense Oligonucleotides The protein is found predominantlyCD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig superfamily containing 2 Ig like domains of the V set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

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