Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization possibly by acting as GEFs

possibly by acting as GEFs

Guanine nucleotide exchange factor (GEF) for RAP1A

Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy)

It interacts with calcium-modulator and cyclophilin ligand (CAML)

The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain

Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization possibly by acting as GEFsFunctions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis