Endoplasmin Polyclonal Antibody, 50ul Subcellular Fractions Alternative splicing results in three

Alternative splicing results in three transcript variants which differ only in the 5' UTR

They are thought to protect their host by lysing cells bearing on their surface ‘nonself’ antigens

Belongs to the small leucine-rich proteoglycan (SLRP) family

The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1

Research studies suggest a role for CD88 in the inflammatory response

Endoplasmin Polyclonal Antibody, 50ul Subcellular Fractions Alternative splicing results in threeHSP90B1 encodes a member of a family of adenosine triphosphate (ATP) metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein (heat shock protein 90 beta family member 1) is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene.