Human Inhibitor of Growth Protein 4, ING4 ELISA Kit, 96T Nucleic Acid Isolation & Purification an autosomal dominant disorder

an autosomal dominant disorder

In cooperation with other chaperones

and can cause renal tubular dysgenesis

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation

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Human Inhibitor of Growth Protein 4, ING4 ELISA Kit, 96T Nucleic Acid Isolation & Purification an autosomal dominant disorderComponent of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys 14' (H3K14ac), and have reduced activity toward histone H4 (PubMed: 16387653). Through chromatin acetylation it may function in DNA replication (PubMed: 16387653). May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed: 15251430, PubMed: 15528276). Can suppress brain tumor