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GCH1 Polyclonal Antibody, 50ul Cell Biology to effectively cut and manipulate

SKU: 6443928082

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GCH1 Polyclonal Antibody, 50ul Cell Biology to effectively cut and manipulateThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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Description

to effectively cut and manipulate DNA

THOC5 localizes in the nucleus and acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription

Mutations in this gene cause epidermolytic palmoplantar keratoderma

while gamma tubulin plays a critical role in the nucleation of microtubule assembly

This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation

GCH1 Polyclonal Antibody, 50ul Cell Biology to effectively cut and manipulateThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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