Shc(Phospho Tyr349) Polyclonal Antibody, 100ul Pathway and Network Analysis the encoded protein binds to

the encoded protein binds to the ER stress response element

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78 kDa glucose-regulated protein encoded by HSPA5 is a member of the heat shock protein 70 (HSP70) family

Although the BCR-ABL fusion protein has been extensively studied

The protein is required for complex I assembly and electron transfer activity

Shc(Phospho Tyr349) Polyclonal Antibody, 100ul Pathway and Network Analysis the encoded protein binds toThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.