LIS1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Diseases associated with PGLS include

Diseases associated with PGLS include lymphatic system disease

Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin

which separates the site of transcription initiation from protein coding sequence

the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding

Microtubule associated proteins regulate the stability of microtubules and control processes such as cell polarity/differentiation

LIS1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Diseases associated with PGLS includeThis locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller Dieker lissencephaly syndrome. This gene encodes the non catalytic alpha subunit of the intracellular Ib isoform of platelet activating factor acteylhydrolase a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN 2 position of platelet activating factor (identified as 1 O alkyl 2 acetyl sn