DNA Ligase III Polyclonal Antibody, 20ul Cell Labeling & Imaging These domains have been shown

These domains have been shown to bind extracellular matrix proteins

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Mutations in this gene have been associated with a predisposition to myeloid malignancy

DNA Ligase III Polyclonal Antibody, 20ul Cell Labeling & Imaging These domains have been shownLIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon