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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection and PRF1 genes

SKU: 57964521074

4.1
USD162.00 USD183.00

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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection and PRF1 genesCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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Description

and PRF1 genes

This highly conserved protein family is found in both plants and mammals| and this protein is 99% identical to the mouse| rat and sheep orthologs

This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens

This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA

Inactivating variants of this gene result in the recessive Lutheran null phenotype

DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection and PRF1 genesCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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