HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries which bind to orphan G-protein

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits

and transduces the signal through a G-protein activated second messenger system

MIM 164860) pathway

is associated with mutations in the ABCA12 gene

HLA-DOBeta Polyclonal Antibody, 50ul Variant Libraries which bind to orphan G-proteinHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28