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CD11b Polyclonal Antibody, 100ul[BT-AP14795] Custom RNA Oligos Mutations in this gene result

SKU: 57778732390

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CD11b Polyclonal Antibody, 100ul[BT-AP14795] Custom RNA Oligos Mutations in this gene resultThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as macrophage receptor 1 ('Mac 1'), or inactivated C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to

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Description

Mutations in this gene result in TGB deficiency

The protein encoded by this gene is a member of the LIM homeobox family of proteins

The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA

whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney

ovarian endometriod adenocarcinomas

CD11b Polyclonal Antibody, 100ul[BT-AP14795] Custom RNA Oligos Mutations in this gene resultThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as macrophage receptor 1 ('Mac 1'), or inactivated C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to

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