SPAK(Phospho Ser309) Polyclonal Antibody, 100ul Cell Culture Plates The protein encoded by this

The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation

Guanine nucleotide-binding protein G(olf) subunit alpha couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system

Belongs to the small leucine-rich proteoglycan (SLRP) family

Mutations in this gene are associated with glutamate formiminotransferase deficiency

Based on studies in chicken and mouse

SPAK(Phospho Ser309) Polyclonal Antibody, 100ul Cell Culture Plates The protein encoded by thisThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the