MED11 Polyclonal Antibody, 50ul Drying & Desiccation CBFA2T3 (CBFA2/RUNX1 translocation partner 3)

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression

Mediates the nuclear import of H2B histone (By similarity)

Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding

This gene uses alternative transcription start sites

Interacts with the N-terminal zinc-finger of GATA1

MED11 Polyclonal Antibody, 50ul Drying & Desiccation CBFA2T3 (CBFA2/RUNX1 translocation partner 3)MED11 is a component of the Mediator complex, which is a coactivator for DNA binding factors that activate transcription via RNA polymerase II (Sato et al., 2003