Skp2 p45 Polyclonal Antibody, 20ul Site-directed Mutagenesis A pseudogene has been identified

A pseudogene has been identified on chromosome 17

NCOR1 (nuclear receptor corepressor 1) encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery

2007 [PubMed 17353262])

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it can function as a co-repressor of androgen-responsive gene expression

Skp2 p45 Polyclonal Antibody, 20ul Site-directed Mutagenesis A pseudogene has been identifiedSKP2 encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: fbws containing WD 40 domains, Fbls containing leucine rich repeats, and Fbxs containing either