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AF-10 Polyclonal Antibody, 50ul Human Genome Knockout Libraries MME encodes a common acute

SKU: 55986487013

4.8
EUR185.00 EUR226.00

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AF-10 Polyclonal Antibody, 50ul Human Genome Knockout Libraries MME encodes a common acuteMLLT10 encodes a transcription factor (myeloid lymphoid or mixed lineage leukemia; translocated to, 10) and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for MLLT10.

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Description

MME encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL)

Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function

Also expressed by dermal Langerhans cells (at protein level)

Histone H3

Not expressed in spleen

AF-10 Polyclonal Antibody, 50ul Human Genome Knockout Libraries MME encodes a common acuteMLLT10 encodes a transcription factor (myeloid lymphoid or mixed lineage leukemia; translocated to, 10) and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for MLLT10.

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