Tak1(Phospho Thr187) Polyclonal Antibody, 100ul Supplements Defects in this gene cause

Defects in this gene cause Hailey-Hailey disease

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Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1

The protein has been implicated in the development of Alzheimer disease

Tak1(Phospho Thr187) Polyclonal Antibody, 100ul Supplements Defects in this gene causeThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL 1 this protein forms a kinase complex including TRAF6 MAP3K7P1 TAB1 and MAP3K7P2 TAB2; this complex is required for the activation of nuclear factor kappa