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GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) |Type IV collagen is the

SKU: 51343089902

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GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) |Type IV collagen is theGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.

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Description

|Type IV collagen is the major structural component of glomerular basement membranes (GBM)| forming a 'chicken-wire' meshwork together with laminins| proteoglycans and entactin/nidogen

p38/MAPK14

The encoded protein is associated with angiogenesis| with potential roles in endothelial tube formation and the migration of endothelial cells

In response to BMP ligands| this protein can be phosphorylated and activated by the BMP receptor kinase

sequence The cDNA appears to contain a duplicated region

GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) |Type IV collagen is theGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.

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